Automated Moving Target Defense (AMTD) is a set of technologies and methods to make unpredictable automated changes to an IT environment, making it significantly harder for attackers to identify and exploit vulnerabilities. AMTD integrates proactive defense mechanisms that continuously alter the IT landscape, automation to seamlessly orchestrate these changes, and deception technologies to mislead attackers. Additionally, it utilizes intelligent change decisions based on threat intelligence and automated responses. By increasing complexity and unpredictability, AMTD enhances the security of endpoints, cloud infrastructure, and other digital assets, providing a robust defense against advanced cyber threats. This approach shifts from traditional detection and response to preemptive defense and unpredictable change.