We use it in a Hub and Spoke setup, you can use Microsoft's private global network which improves reliability.

There are a few starting points - it works and it is fairly easy to use for this direct purpose. But, it is not on par with other similar solutions, private and public address mixups are quite easy and this stems from the actual design of the whole Cloud solution by MS - at least we were told that. Some elements like external route handling can be done better and a few leftovers cost us dearly during migrations.